ABO血型与静脉血栓栓塞症关系的研究进展

Research progress on relationships of ABO blood types with venous thromboembolism

  • 摘要: 静脉血栓栓塞症(VTE)是临床常见疾病, 也是心血管系统发病率排名第三的重大疾病。深静脉血栓若继发肺栓塞,将导致死亡率显著升高。若治疗不规范,深静脉血栓可发展为血栓形成后综合征。ABO血型与VTE及其预后关系密切,非O型血个体似乎更易发生VTE且预后更差,但相关研究的样本人群特征变化较大且结论不一。本研究对ABO血型与VTE及其预后相关性的最新国内外文献进行综述,分析得出在治疗VTE患者时,应将血型纳入影响疗效的因素中来综合考虑,为不同血型患者提供更加个体化的VTE防治方案。

     

    Abstract: Venous thromboembolism (VTE) is a common clinical disease and the third major diseases of cardiovascular system. If deep venous thrombosis is secondary to pulmonary embolism, it will lead to a significant increase in mortality. If the nonstandard treatment is performed, deep venous thrombosis may develop into post-thrombotic syndrome. ABO blood types are closely related to VTE and its prognosis, individuals with non-O blood type seem to be more prone to occur VTE and worse prognosis, but the characteristics of the sample population in relevant studies vary greatly and the conclusions are different. This study reviewed the latest domestic and foreign literatures on the correlations of ABO blood types with VTE as well as its prognosis, and it is concluded that when treating VTE patients, blood group should be integrated into the factors affecting the curative effect, so as to provide more individualized VTE prevention and treatment schemes for patients with different blood types.

     

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