电针结合加味桑螵蛸汤治疗女性膀胱过度活动症的临床研究

Clinical study of electroacupuncture combined with supplemented Sangpiaoxiao Decoction in treatment of female overactive bladder

  • 摘要:
      目的  观察电针结合加味桑螵蛸汤治疗女性膀胱过度活动症(OAB)的临床疗效。
      方法  选取64例符合OAB诊断标准的患者为研究对象, 随机分为治疗组和对照组,每组32例。对照组采用口服酒石酸托特罗定片治疗,治疗组在对照组基础上加用电针穴位治疗及口服加味桑螵蛸汤,每周治疗3次,共治疗6周。比较治疗前和治疗3、6周后, 2组膀胱过度活动症评分(OABSS)、生活质量评估表(QOL)评定情况。比较2组治疗前、治疗6周后排尿日志,并进行中医疗效评价。
      结果  治疗3、6周后,治疗组OABSS、QOL评分均低于对照组,临床总有效率高于对照组,差异有统计学意义(P<0.05)。治疗6周后,治疗组夜尿次数和急迫性尿失禁(UUI)次数少于对照组,差异有统计学意义(P<0.05)。
      结论  电针结合加味桑螵蛸汤治疗女性OAB患者,可在一定程度上改善其临床症状及生活质量。

     

    Abstract:
      Objective  To observe the clinical effect of electroacupuncture combined with supplemented Sangpiaoxiao Decoction in treatment of female overactive bladder (OAB).
      Methods  Sixty-four patients who met OAB diagnostic criteria were selected as the study subjects, and randomly divided into treatment group and control group, with 32 cases in each group. The control group was treated with oral treatment of tolterodine tartrate tablets, and the treatment group was additionally treated with electric acupuncture point treatment and oral treatment of supplemented Sangpiaoxiao Decoction, the patients were treated three times a week for a total of 6 weeks. The overactive bladder symptom score (OABSS) and quality of life (QOL) score before treatment were compared with 3, 6 weeks after treatment in the two groups. The urination logs of the two groups were compared before treatment and 6 weeks after treatment, and the TCM efficacy was evaluated.
      Results  After 3 and 6 weeks of treatment, OABSS and QOL scores in the treatment group were significantly lower, and the total clinical response rate was significantly higher than that in the control group (P < 0.05). After 6 weeks of treatment, the nocturnal urination times and urge urinary incontinence (UUI) times in the treatment group were significantly less than those in the control group (P < 0.05).
      Conclusion  Electroacupuncture combined with supplemented Sangpiaoxiao Decoction can improve the clinical symptoms and quality of life in female patients with OAB to certain extent.

     

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