Objective  To explore the influencing factors of complications in early esophageal cancer and precancerous lesions after endoscopic treatment.

  Methods  A total of 268 patients with early esophageal cancer or precancerous lesions who underwent endoscopic treatment were selected as research objects, their clinical data were retrospectively analyzed, and the influencing factors of related complications were analyzed by univariate and multivariate Logistic regression analysis.

  Results  A total of 69 cases (with the overall complication rate of 25.75%) of 268 patients had complications, including delayed bleeding in 11 cases (4.10%), esophageal perforation in 12 cases (4.48%), and esophageal stenosis in 46 cases (17.16%). Univariate and multivariate Logistic regression analysis showed that lesion diameter and lesion circumference were independent influential factors of delayed postoperative bleeding (P < 0.05), surgical method was independent influential factors of esophageal perforation (P < 0.05), lesion circumference and operative time were independent influential factors of esophageal stenosis (P < 0.05).

  Conclusion  Patients with early esophageal cancer and precancerous lesions are prone to occur delayed bleeding, esophageal perforation and esophageal stenosis after endoscopic treatment, among which the independent influencing factors of delayed bleeding are lesion diameter and lesion circumference, the independent influencing factors of esophageal perforation are lesion circumference and operative time. In order to improve the prognosis and quality of life of patients, surgeons should take corresponding preventive measures according to the influencing factors of complications.