Objective  To explore clinical effect of neuroendoscopy assisted multi-technology in combination in keyhole retrosigmoid approach(RSA) of acoustic neuroma resection.

  Methods  A total of 84 patients with AN underwent keyhole RSA resection were selected as study subjects. According to different surgical methods, they were divided into control group (40 cases) and observation group (44 cases).The control group was treated with traditional microscope resection, and the observation group was treated with neuroendoscope assisted microscope resection combined with neuroelectrophysiological monitoring and ultrasonic bone knife technique. Total resection rate, facial nerve function retention rate and postoperative complications were compared between the two groups.

  Results  The total resection rate of tumor in the observation group was significantly higher than that in the control group (P < 0.05). Six months after surgery, the facial nerve function retention rate in the observation group was significantly higher than that in the control group (P < 0.05). The total incidence of postoperative complications in the observation group was 6.8%, which was significantly lower than 22.5% in the control group (P < 0.05).

  Conclusion  Neuroendoscopy assisted multi-technologycombination in retrosigmoid keyhole approach of AN resection can effectively improve the total tumor resection rate and reduce intraoperative facial nerve injury. It has better effect on facial nerve function preservation after operation and can reduce the total incidence of postoperative complications.