云南省保山地区泌尿系结石成分分析

Composition analysis of urinary stones in Baoshan District of Yunnan Province

  • 摘要:
      目的  探讨云南省保山地区不同泌尿系结石成分的分布特征及可能形成的因素。
      方法  收集1 710例泌尿系结石样本及患者的临床资料,使用红外光谱自动分析系统对结石样本进行成分分析,比较不同结石成分在患者不同性别、部位和年龄的分布情况。
      结果  1 710例患者中,单一成分结石(6种,1 153例)和混合成分结石(20种,557例)均以草酸钙为主。保山地区男性患者单一成分结石和草酸钙结石占比高于女性,女性患者碳酸磷灰石及磷酸铵镁结石占比高于男性,差异有统计学意义(P < 0.05);不同性别无水尿酸成分结石比较,差异无统计学意义(P>0.05)。草酸钙在上尿路结石中较为常见,而无水尿酸、磷酸铵镁及尿酸铵结石在下尿路中更为多见(P < 0.05)。D-J管附着石壳中草酸钙结石占比低于上尿路结石,但磷酸铵镁结石占比高于上尿路结石,差异有统计学意义(P < 0.016 67)。草酸钙结石多见于青壮年患者(31~45岁),而尿酸结石发生率随年龄的增长而增高,且常见于45岁左右患者,而碳酸磷灰石常见于30岁左右患者(P < 0.005)。
      结论  云南省保山地区不同结石成分在不同性别、部位和年龄分布上有一定差异,且存在独特的分布特征。

     

    Abstract:
      Objective  To explore the characteristics of different compositions of urinary stones in Baoshan District of Yunnan Province, and the possible formative factors of different types of stones in this region.
      Methods  A total of 1 710 urinary stone samples and the clinical data of patients were collected. The composition of the stone samples was analyzed by using the automatic infrared spectrum analysis system, and the distribution of different stone components in patients with different genders, locations and ages was compared.
      Results  Among the 1 710 patients, pure-component stones (6 types, 1 153 cases) and mixed-component stones (20 types, 557 cases) were dominated by calcium oxalate. The proportions of pure-component stones and calcium oxalate stones of the males in Baoshan district were higher than that of the females, and the proportions of apatite carbonate and magnesium ammonium phosphate stones in female patients were higher than those in male patients (P < 0.05). There was no difference in anhydrous uric acid stonesin different genders(P>0.05). Calcium oxalate was more commonly seen in upper urinary stones, while anhydrous uric acid, magnesium ammonium phosphate, and ammonium urate stones were more commonly seen in the lower urinary tract (P < 0.05). The proportion of calcium oxalate stones in D-J tube attached stone shell was lower than that in upper urinary tract stones, but the proportion of magnesium ammonium phosphate stones was higher than that in upper urinary tract stones (P < 0.016 67). Calcium oxalate stones were more common in young adults (31 to 45 years old), the incidence of uric acid stones increased with growing of age, and was more frequently observed in patients aged 45 years old, and carbonate apatite was commonly seen in patients aged 30 years old (P < 0.005).
      Conclusion  There are significant differences in the distribution of stone components in different genders, locations, and ages in Baoshan District of Yunnan Province, and there are unique distribution characteristics.

     

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