Objective   To explore the influence of medication education combined with information follow-up on therapeutic effect in patients with type 2 diabetes mellitus (T2DM) in clinic.

  Methods   A total of 199 patients with T2DM were randomly divided into observation group with 100 cases and control group with 99 cases. The patients in the control group were treated with routine treatment, while the patients in the observation group were treated with medication education and information follow-up by clinical pharmacists on the basis of routine treatment. After 6 months of intervention, the biochemical indexes such as blood pressure, blood lipid and blood sugar were compared between the two groups.

  Results   After 6 months of intervention, the fasting blood glucose, glycosylated hemoglobin, systolic blood pressure, diastolic blood pressure, high-density lipoprotein, triglyceride and total cholesterol in the observation group were significantly lower than those before intervention, while the body mass index, the ratio of patients with glycosylated hemoglobin less than 7% and the standard rate of blood pressure were significantly higher than those before treatment (P < 0.05). After 6 months of intervention, the diastolic blood pressure, low-density lipoprotein, total cholesterol and body mass index in the control group were significantly higher than those before treatment (P < 0.05). After 6 months of intervention, the fasting blood glucose, glycosylated hemoglobin and total cholesterol in the observation group were significantly lower than those in the control group, while the ratio of patients with glycosylated hemoglobin less than 7% and the standard rate of blood pressure were significantly higher than those in the control group (P < 0.05). After the intervention, the score of medication compliance in the observation group was (0.32±0.11), which was significantly lower than (0.77±0.65) in the control group (P < 0.05).

  Conclusion   Regular medication education and information follow-up by clinical pharmacists for T2DM patients can improve the standard rates of blood glucose, blood lipid and medication compliance, and strengthen the therapeutic effect.