Objective  To explore the effect of bronchial blocker (BB) positioning in patients undergoing one-lung ventilation (OLV).

  Method  A total of 166 OLV patients were selected and divided into observation grouppositioning of the change of peak airway pressure (P_peak) difference, n=81 and control group (positioning of fiberoptic bronchoscopy, n=85) according to different positioning methods. The positioning effects of the two groups were compared.

  Results  There were no significant differences in the success rate of positioning and intubation time between the observation group and the control group (P>0.05). The positioning time was shorter and total incidence of adverse reactions in the observation group were significantly lower than those in the control group (P < 0.05). At the time points of undergoing double lung ventilation after confirming the correct position of the cuff (T₁), undergoing OLV after confirming the correct position of the cuff (T₂), undergoing OLV when the cuff was inserted into deep position of the bronchus (T₃), and undergoing OLV when the cuff returned to the opening of the bronchus in the shallow position of the tube (T₄), P_peak and plateau pressure (P_plat) of the observation group were significantly lower, and dynamic Compliance (C_dyn) was significantly higher than that of the control group (P < 0.05). At T₃, mean arterial pressure (MAP) and heart rate (HR) of the observation group were significantly lower, and the oxygen saturation (SpO₂) was significantly higher than that of the control group (P < 0.05).

  Conclusion  Compared with fibrobronchial positioning, BB positioning can be applied in OLV patients with faster positioning and higher safety, which can effectively reduce stress response.