学龄前患儿腺样体肥大切除术全身麻醉苏醒期不良事件的发生情况及其影响因素

Occurrence of adverse events and its influencing factors during recovery period of general anesthesia in preschool children with resection of adenoid hypertrophy

  • 摘要:
      目的  观察学龄前患儿腺样体肥大(AH)切除术全身麻醉苏醒期不良事件发生情况,并分析其影响因素。
      方法  回顾性分析160例择期行AH切除术的学龄前患儿的资料,统计患儿全身麻醉苏醒期不良事件发生情况,采用Logistic回归分析筛选、确定学龄前患儿AH切除术全身麻醉苏醒期不良事件发生的影响因素,并探讨可能的发生机制。
      结果  160例择期行AH切除术学龄前患儿中,全身麻醉苏醒期不良事件患儿34例(21.25%)。初步比较发生与未发生全身麻醉苏醒期不良事件的患儿基线资料,并经Logistic回归分析检验结果显示,苏醒期仰卧位、使用七氟醚均是学龄前患儿AH切除术全身麻醉苏醒期不良事件发生的影响因素(OR>1,P < 0.05),而使用右美托咪定是患儿全身麻醉苏醒期不良事件发生的保护因素(OR < 1,P < 0.05)。
      结论  学龄前患儿AH切除术全身麻醉苏醒期有一定不良事件发生风险,可能与苏醒期仰卧位、使用七氟醚有关,而使用右美托咪定可能会减少不良事件的发生。

     

    Abstract:
      Objective  To observe the occurrence of adverse events during recovery period of general anesthesia in preschool children with resection of adenoid hypertrophy (AH) and to analyze its influencing factors.
      Methods  The data of 160 preschool children undergoing elective AH resection was retrospectively analyzed, the occurrence of adverse events in children during the recovery period of general anesthesia was analyzed. Logistic regression analysis was used to screen and determine the influencing factors of adverse events during the recovery period of general anesthesia in preschool children with AH resection, and the possible mechanism was also discussed.
      Results  Among 160 preschool children who undergo elective AH resection, 34 cases occurred adverse events during the recovery period of general anesthesia, accounting for 21.25%. After preliminary comparing the baseline data of children with and without adverse events during the recovery period of general anesthesia and Logistic regression analysis, the results showed that supine position during anesthesia recovery period and use of sevoflurane were the influencing factors of adverse events during recovery period of general anesthesia in preschool children with AH resection (OR>1, P < 0.05), while the use of dexmedetomidine was a protective factor for adverse events in children during the recovery period of general anesthesia (OR < 1, P < 0.05).
      Conclusion  There is a certain risk of adverse events during the recovery period of general anesthesia in preschool children with AH resection, which may be related to supine position during recovery period and use of sevoflurane, while the use of dexmedetomidine may reduce the occurrence of adverse events.

     

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