Abstract:
Objective To analyze the correlations between routine coagulation test indexes and thromboelastography parameters in patients with acute myocardial infarction.
Methods Totally 100 patients with acute myocardial infarction were selected as study group, while another 100 healthy volunteers in the same period were selected as control group. The routine coagulation test indexes and thromboelastography parameters were compared between two groups, and the correlation between the two methods was analyzed.
Results The thrombin time of the study group was significantly longer, and fibrinogen level of the study group was significantly higher than that of the control group (P < 0.05). The coagulation reaction time (R value) and clot formation time (K value) of the study group were significantly shorter than those of the control group, while the clot formation rate (α value) and the maximum amplitude (MA) after clot formation were higher than those in the control group (P < 0.05). Prothrombin time and activated partial thromboplastin time were positively correlated with R value and negatively correlated with MA value and α value of thromboelastography, but had no correlations with K value. Thrombin time and fibrinogen were negatively correlated with K value and positively correlated with α value and MA value, and at the same time, fibrinogen was negatively correlated with R value.
Conclusion There are significant correlations between routine coagulation test indexes and thromboelastography parameters in patients with acute myocardial infarction. The guidance effect of combining routine coagulation test indexes with thromboelastography is better.
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