黄柏红花散对抗肿瘤药物相关静脉炎的预防效果

Effect of Huangbai Honghua Powder in preventing antitumor drug-related phlebitis

摘要:
目的观察黄柏红花散对抗肿瘤药物相关静脉炎的预防效果。
方法将270例使用抗肿瘤药物患者随机分为3组，A组采用黄柏红花散外敷，B组采用尤卓尔外涂，C组采用尤卓尔涂抹联合黄柏红花散外敷，每组90例。观察3组静脉炎发生率及疼痛发生情况。
结果 C组静脉炎发生率与疼痛发生率与A组和B组比较，差异均有统计学意义（P < 0.05）。
结论尤卓尔联合黄柏红花散可有效预防抗肿瘤药物相关静脉炎的发生，且联合用药效果更佳。

Abstract:
Objective To observe effect of Huangbai Honghua Powder in preventing phlebitis caused by antitumor drugs.
Methods A total of 270 patients using anti-tumor drugs were randomly divided into three groups. A group (n=90) used Huangbai Honghua Powder for external application, B group (n=90) used hydrocortisone butyrate cream for external application, and C group (n=90) used external application of hydrocortisone butyrate cream and Huangbai Honghua Powder. The incidence of phlebitis and the occurrence of pain in the three groups were observed.
Results The incidence rates of phlebitis and pain in the group C showed significant differences when compared with those in the groups A and B (P < 0.05).
Conclusion External application of hydrocortisone butyrate cream and Huangbai Honghua Powder can effectively prevent the occurrence of antitumor drug-related phlebitis, and is higher in safety.