Peek Prevail椎间融合器治疗颈椎间盘退行性疾病的效果研究

Effect of Peek Prevail intervertebral fusion devicein treatment of patients with degenerative disease of cervical intervertebral disc

  • 摘要:
      目的  观察Peek Prevail椎间融合器治疗颈椎间盘退行性疾病的效果。
      方法  选取2017年1—6月本院行颈椎前路减压融合术(ACDF)中使用Peek Prevail椎间融合器的31例患者为Prevail组,至少随访2年。另选取同期使用前路钢板治疗的31例患者为钢板组。比较2组患者手术后影像学变化及术后并发症发生情况。
      结果  Prevail组术中失血量少于钢板组,手术时间均短于钢板组,差异有统计学意义(P < 0.05)。钢板组9例患者术后发生吞咽困难,其中4例患者直至随访结束时仍表现出轻度吞咽困难;Prevail组6例患者出现轻度吞咽困难,且症状在术后6周内完全消失。2组术后各时间点的颈椎前凸角、手术节段Cobb角和椎间隙高度均较术前增高,差异有统计学意义(P < 0.01)。
      结论  与传统前路钢板相比,Peek Prevail椎间融合器具有术后吞咽困难的发生风险低、手术时间短、失血量少等优点,可以获得更好的治疗效果。

     

    Abstract:
      Objective  To observe the effect of Peek Prevail intervertebral fusion device in the treatment of patients with degenerative disease of cervical intervertebral disc.
      Methods  From January to June 2017, 31 patients with anterior cervical decompression and fusion (ACDF) by Peek Prevail intervertebral fusion device in author's hospital were selected as Prevail group, and all the patients were followed up for at least 2 years. Another 31 patients treated with anterior plate in the same period were selected as the plate group. The imaging changes and postoperative complications were compared between the two groups.
      Results  The intraoperative blood loss and operation time in the Prevail group were significantly less and shorter than those in the plate group (P < 0.05). There were 9 patients with dysphagia in the plate group, and 4 of them had mild dysphagia until the end of follow-up. There were 6 patients with mild dysphagia in the Prevail group, and their symptoms disappeared completely within 6 weeks after operation. The cervical lordosis angle, Cobb angle of surgical segment and intervertebral space height at each time point after operation in both groups were significantly higher than those before operation (P < 0.01).

     

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