Objective  To investigate the related factors of mycoplasma pneumoniae pneumonia (MPP) complicated with pleural effusion in children.

  Methods  A total of 386 children with MMP were divided into observation group (complicated with pleural effusion, n=168) and control group (without pleural effusion, n=218) according to the imaging results. The risk factors of MPP combined with pleural effusion were analyzed. The changes of laboratory examination indexes between the two groups were observed.

  Results  The age of the observation group was significantly higher, the heat course, hospitalization time, macrolides use time were significantly longer, and the number of glucocorticoid use cases was significantly more than that of the control group (P < 0.05). White blood cells (WBC) count, neutrophil percentage (N), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), calcitonin (PCT) and immunoglobulin A (IgA), immunoglobulin G (IgG) were significantly higher than that of control group, serum total protein (TP), albumin (AP) in the observation group were significantly lower than those in the control group (P < 0.05). ESR, PCT and TP levels were independent risk factors for MPP complicated with pleural effusion (P < 0.05).

  Conclusion  MPP combined with pleural effusion in children has a variety of related influencing factors, and the increase of age, the increase of ESR and PCT, and the decrease of TP indicate the increased risk of pleural effusion in children.