基于关联规则的新型冠状病毒肺炎相关中药发明专利组方分析

Analysis of prescription of Coronavirus Disease 2019 related traditional Chinese medicine patent for invention based on association rules

  • 摘要:
      目的  分析用于防治新型冠状病毒肺炎的中药专利组方用药规律,为相关中药组方研发及相关专利的申请提供参考。
      方法  在专利检索系统中检索相关中药专利,频数分析及分类各中药,并对专利组合物中高频中药进行关联网络分析。
      结果  筛选获得46件中药组合物专利,涉及中药124味,中药使用的总频次为552次。使用频次超过10的中药有18味,符合二、三项关联规则的药味分别有11、12味。
      结论  防治新型冠状病毒肺炎常用清热、解表、止咳化痰、平喘、化湿类中药。

     

    Abstract:
      Objective  To analyze the rules of drug use of Chinese medicinal patent formulas for the prevention and treatment of Coronavirus Disease 2019, and to provide reference for the development of related formulas of Chinese medicine and the application of related patent for invention.
      Methods  The relevant Chinese medicine patents were retrieved in the patent retrieval system, frequency analysis and classification of each herb were carried out, and the association network analysis of high frequency Chinese herbs in patent compositions was carried out.
      Results  A total of 46 traditional Chinese medicine prescriptions were screened and obtained, involving 124 traditional Chinese herbs, and the total frequency of use of traditional Chinese medicine were 552 times. There were 18 traditional Chinese herbs used more than 10 times, and there were 11 and 12 herbs in accordance with the two and three association rules, respectively.
      Conclusion  Traditional Chinese herbs with the functions of clearing heat, relieving exterior syndromes, relieving cough and eliminating phlegm, relieving asthma, reducing dampness are commonly used to prevent and treat Coronavirus disease 2019.

     

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