Value of blood urea nitrogen combined with model of obesity related status in evaluating prognosis of acute pancreatitis
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摘要: 目的 探讨急性胰腺炎(AP)患者预后与尿素氮(BUN)及肥胖相关状态(ORS)的相关性。 方法 回顾性分析300例AP患者的临床资料,分析BUN联合ORS模型与轻症急性胰腺炎(MAP)及重症急性胰腺炎(SAP)预后不良因素的相关性。 结果 BUN、体质量指数(BMI)和糖化血红蛋白(HbAlc)与AP预后不良的发生率呈显著正相关(P<0.05)。BUN及空腹血糖(FBG)升高与AP进展呈显著正相关(P<0.05)。BUN升高合并ORS时, AP患者的并发症发生率、重症比率及死亡风险显著增高。BUN联合ORS模型的评价效果优于单指标模型。 结论 BUN联合ORS模型在早期评估AP预后中有一定的价值,相关指标数值的升高提示预后不良。Abstract: Objective To explore the correlations between the prognosis of patients with acute pancreatitis(AP)and blood urea nitrogen(BUN)as well as obesity related status(ORS). Methods The clinical materials of 300 AP patients were analyzed retrospectively. The correlations between BUN combined with ORS model and adverse prognostic factors of mild acute pancreatitis(MAP)as well as severe acute pancreatitis(SAP)were analyzed. Results BUN, body mass index(BMI)and glycosylated hemoglobin(HbA1c)were positively correlated with the incidence of adverse prognosis in AP patients(P<0.05). There was a significant positive correlation between the increase of BUN, fasting blood glucose(FBG)and the progression of AP(P<0.05). The incidence of complications, ratio of critical illness and death risk in AP patients were significantly increased when increased BUN combined ORS was existed. The evaluation effect of BUN combined with ORS model was better than that of single index model. Conclusion BUN combined with ORS model has a certain value in early evaluation of prognosis of AP patients, and the increase of related index value indicates a poor prognosis.
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