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柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果

卫坚, 杨向利

卫坚, 杨向利. 柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果[J]. 实用临床医药杂志, 2020, 24(21): 43-45,49. DOI: 10.7619/jcmp.202021013
引用本文: 卫坚, 杨向利. 柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果[J]. 实用临床医药杂志, 2020, 24(21): 43-45,49. DOI: 10.7619/jcmp.202021013
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WEI Jian, YANG Xiangli. Effect of supplemented Chaihu Guizhi Longgu Muli Decoction in treatment of insomnia induced by anxiety in perimenopausal period[J]. Journal of Clinical Medicine in Practice, 2020, 24(21): 43-45,49. DOI: 10.7619/jcmp.202021013
Citation: WEI Jian, YANG Xiangli. Effect of supplemented Chaihu Guizhi Longgu Muli Decoction in treatment of insomnia induced by anxiety in perimenopausal period[J]. Journal of Clinical Medicine in Practice, 2020, 24(21): 43-45,49. DOI: 10.7619/jcmp.202021013
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柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果

  • 陕西省渭南市蒲城县医院, 1. 老年病科, 2. 药剂科, 陕西 渭南, 715500

基金项目: 

陕西省渭南市卫健委计划项目(2020PSL029)

详细信息
    通讯作者:

    杨向利, E-mail: 632970915@qq.com

  • 中图分类号: R271.11

Effect of supplemented Chaihu Guizhi Longgu Muli Decoction in treatment of insomnia induced by anxiety in perimenopausal period

  • 1. Geriatrics Department, 2. Pharmacy Department, Pucheng County Hospital in Weinan City of Shaanxi Province, Weinan, Shaanxi, 715500

摘要

    摘要
  • 摘要: 目的 观察柴胡桂枝龙骨牡蛎汤加味治疗围绝经期焦虑性失眠的效果。 方法 选取本院接诊的300例围绝经期女性焦虑性失眠患者作为研究对象,按照随机数表法将其分为研究组和对照组,每组150例。对照组采用常规治疗,研究组采用柴胡桂枝龙骨牡蛎汤加味治疗。比较2组治疗前后绝经综合征症状评定量表(Kupperman)评分、中医证候评分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、匹兹堡睡眠质量指数(PSQI)评分及治疗效果,并记录2组的入睡时间和睡眠时间。 结果 研究组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后, 2组Kupperman评分、中医症候评分、SAS、SDS指标数值均下降,且研究组以上指标均低于对照组,差异有统计学意义(P<0.05)。 治疗前, 2组PSQI评分、入睡时间、睡眠时间比较,差异无统计学意义(P>0.05); 治疗后,研究组PSQI评分低于对照组,入睡时间短于对照组,睡眠时间长于对照组,差异均有统计学意义(P<0.05)。 结论 柴胡桂枝龙骨牡蛎汤加味治疗围绝经期女性焦虑性失眠的效果显著,可有效改善睡眠质量和抑郁、焦虑情绪,缩短入睡时间,延长睡眠时间。
    Abstract: Objective To observe effect of supplemented Chaihu Guizhi Longgu Muli Decoction in treatment of insomnia induced by anxiety in perimenopausal period. Methods A total of 300 female perimenopausal patients with insomnia induced by anxiety were selected as research objects. According to random number table method, they were divided into study group and control group, with 150 cases in each group. The control group was given conventional treatment, and the study group was treated with supplemented Chaihu Guizhi Longgu Muli Decoction. Kupperman Menopausal Index(Kupperman)score, traditional Chinese medicine symptom score, Self-rating Anxiety Scale(SAS)score, Self-rating Depression Scale(SDS)score, Pittsburgh Sleep Quality Index(PSQI)score, falling asleep time, sleep duration before and after treatment as well as treatment effect were compared and recorded. Results The total effective rate of the study group was significantly higher than that of the control group(P<0.05). After treatment, Kupperman score, traditional Chinese medicine symptom, SAS and SDS scores of the two groups were significantly declined, and were significantly lower in study group than those of the control group(P<0.05). Before treatment, there were no significant differences in PSQI score, falling asleep time, sleep duration between the two groups(P>0.05). After treatment, the PSQI score was lower, and falling asleep time was significantly shorter, and sleep - time was significantly longer than that of the control group(P<0.05). Conclusion Chaihu Guizhi Longgu Muli Decoction has a remarkable effect in perimenopausal women with anxiety induced insomnia, which can effectively improve the sleep quality, depression and anxiety, shorten the falling asleep time and prolong sleep duration.
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    • 参考文献(18)
  • 许晓伍, 黄妙纯, 刘凤岚, 等. 失眠的病因学研究进展[J]. 世界睡眠医学杂志, 2017, 4(5): 307-312.
    刘剑锋, 孟凡萍, 周一心. 失眠与抑郁的相关性研究进展[J]. 中国医药导报, 2019, 16(1): 45-48.
    高黎妮, 高林娟, 吴静. 围绝经期妇女失眠症患者就医行为、个性特征和心理健康状况研究[J]. 实用临床医药杂志, 2018, 22(14): 101-104.
    赵静, 陆颖, 吕钦谕, 等. 慢性失眠患者认知功能、生活质量的研究[J]. 精神医学杂志, 2016, 29(5): 321-324.
    陈君臻, 滕晶. 焦虑性失眠症临床用药规律分析[J]. 吉林中医药, 2017, 37(7): 727-728

    , 756.
    吴文源, 魏镜, 陶明. 综合医院焦虑抑郁诊断和治疗的专家共识[J]. 中华医学杂志, 2012, 92(31): 2174-2181.

    ZUNG WW. A rating instrument for anxiety disorders[J]. Psychosomaties, 1971, 12: 371-379.

    ZUNG WW, RIEHARDS C B, SHORT M J. Self-rating depression scale in a outpatient clinic. Further validation of the SDS[J]. Arch Gen Psychiatry, 1965, 13: 508-515.

    BUYEE D J, REYNOLDS C F, MONK T H, et al. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research[J]. Psychiatry Research, 1989, 28(2): 193-213.
    叶增杰, 梁木子, 胡蕖, 等. 失眠障碍的国内外研究进展[J]. 医学与哲学, 2017, 38(5): 60-63.

    BLAKE M J, TRINDER J A, ALLEN N B. Mechanisms underlying the association between insomnia, anxiety, and depression in adolescence: Implications for behavioral sleep interventions[J]. Clin Psychol Rev, 2018, 63: 25-40.
    伍亚男, 范颖, 符文彬. 针灸治疗围绝经期失眠症的现代文献研究[J]. 上海针灸杂志, 2016, 35(7): 893-898.
    胡冬梅, 金晓茜, 贺晓梅. 重症肌无力患者抑郁、焦虑、失眠症状发生率以及影响因素研究[J]. 中国临床医生杂志, 2016, 44(1): 36-38.
    程德均. 失眠的中西医诊疗研究进展[J]. 世界最新医学信息文摘, 2019, 19(16): 74-75.
    李丽. 中西医结合治疗对焦虑性失眠患者的临床疗效观察[J]. 临床医药文献电子杂志, 2019, 6(87): 33-35.
    岳慈, 任紫茹, 周素彩, 等. 柴胡加龙骨牡蛎汤加减联合小剂量劳拉西泮治疗焦虑性失眠症疗效观察[J]. 实用临床医药杂志, 2017, 21(17): 179-180.
    刘旭昭, 林芳冰, 马丽然. 柴胡桂枝龙骨牡蛎汤合甘麦大枣汤治疗围绝经期焦虑性失眠临床观察[J]. 中国药物与临床, 2019, 19(9): 1418-1420.
    张东兰. 柴胡桂枝龙骨牡蛎汤加减治疗焦虑抑郁状态型失眠疗效观察[J]. 临床医药文献电子杂志, 2017, 4(23): 4369-4372.
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出版历程
  • 收稿日期:  2020-09-07
  • 网络出版日期:  2020-12-21
  • 发布日期:  2020-11-23

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