Abstract:
Objective To investigate the clinical characteristics and 1-year prognosis of young and middle-aged as well as elderly patients with acute mild cerebral infarction (AMCI) in Xi'an area.
Methods Clinical materials of AMCI patients in 4 grade Ⅲ level A hospitals in Xi'an area were collected. According to differed ages, the patients were divided into elderly group (aged 65 years and above) and young and middle-aged group (age of 18 to less than 65 years). Clinical materials of the two groups were compared. The outcome events of 1-year follow up were recorded, and univariate and multivariate regression analyses were used to investigate 1-year prognosis of patients in both groups.
Results A total of 933 patients with AMCI were included in this study, including 444 cases in the elderly group and 489 cases in the young and middle-aged group. There were significant differences in age, gender, education level, smoking, drinking, body mass index, history of stroke, pneumonia, hypertension, atrial fibrillation, triglyceride, high density lipoprotein, creatinine and urea nitrogen between the young and middle-aged group and the elderly group (P < 0.05 or P < 0.01). After adjustment for the confounding factors, multivariate regression analysis showed that compared to the young and middle-aged group, the risk of 1-year disability in the elderly group significantly increased (HR=3.39, 95%CI, 1.91 to 6.03, P < 0.001).
Conclusion There are significant differences in clinical characteristics in young as well as middle-aged patients with AMCI in Xi'an area. Clinicians should focus on prevention of AMCI in the elderly people, and the effective prevention and treatment measures should be given to improve the prognosis of AMCI patients.
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