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经鼻高流量氧疗在体外循环下冠状动脉旁路移植术后的临床应用

Clinical application of high flow nasal cannula oxygenation therapy in post coronary artery bypass grafting in patients with cardiopulmonary bypass

    摘要
  • 摘要: 目的 观察经鼻高流量氧疗(HFNC)在体外循环下冠状动脉旁路移植术后的应用效果。 方法 回顾性分析体外循环下冠状动脉旁路移植术患者560例的临床资料,其中拔除气管导管后予以面罩吸氧的213例为对照组,拔除气管导管后予以HFNC治疗的347例患者为观察组。比较2组患者氧疗前后不同时点的氧合指数、二次插管率、ICU住院时间、血气分析及脑钠肽(BNP)、心肌肌钙蛋白T(cTnT)等指标。 结果 治疗后,观察组氧合指数、二次插管率、BNP、cTnT、平均ICU住院时间与对照组比较,差异有统计学意义(P< 0.05)。 结论 HFNC能明显改善冠状动脉旁路移植术患者术后氧合能力和心功能,有效预防肺部并发症的发生,缩短ICU住院时间。

     

    Abstract: Objective To observe the efficacy of high flow nasal cannula(HFNC)oxygenation therapy in post coronary artery bypass grafting in patients with cardiopulmonary bypass. Methods The clinical data of 560 patients underwent coronary artery bypass grafting was retrospectively andyzed, among whom 213 patients treated with mask oxygen-inspiration after extubation of tracheal tube were included into control group, and the other 347 patients treated with HFNC after extubation of tracheal tube were selected as observation group. Oxygenation index, secondary intubation rate, ICU stay, blood gas analysis, brain natriuretic peptide(BNP), and cardiac troponin T(cTnT)at different time points before and after oxygen therapy were compared between two groups. Results Oxygenation index, secondary intubation rate, BNP, cTnT, and ICU stay in two groups after treatment showed significant differences(P<0.05). Conclusion HFNC can significantly improve the oxygenation ability and cardiac function of CABG patients after operation, effectively prevent the occurrence of pulmonary complications and shorten the duration of ICU stay.

     

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