Abstract: Objective To observe the effects of neuromuscular electrical stimulation(NMES)combined with early rehabilitation training on rehabilitation after arthroscopic anterior cruciate ligament(ACL)reconstruction. Methods According to random digital table method, 64 patients undergoing arthroscopic ACL reconstruction were randomly divided into two groups. The patients in the control group(n=32)were given early rehabilitation training after operation, and the observation group(n=32)were treated with NMES rehabilitation combined with early rehabilitation training, and the treatment was lasted for 3 months in both groups. Lysholm score, joint motion measuring ruler, and visual analogue score(VAS)were applied to evaluate knee function, knee mobility, and knee comfort before and after 1 month, 2 and 3 months of operation. Results There were no significant differences in Lysholm score and knee joint activity between the two groups before surgery(P>0.05). Lysholm score and knee joint activity degree at 1 month, 2 months, and 3 months after operation were significantly higher and more than those before the operation in two groups(P<0.05), and with the extension of the follow-up time, the above-mentioned indicators showed significant improvement, and observation group showed significant changes when compared to the control group(P<0.05). There was no significant difference in VAS scores before surgery between the two groups(P>0.05), and the VAS scores at 1 month 2 and 3 months after surgery were significantly lower in the two groups than operation before, and observation group was significantly lower than the control - group(P<0.05). The VAS score decreased significantly with the extension of the follow-up time in two group(P<0.05). Conclusion NMES combined with early rehabilitation training can significantly improve knee function and knee joint mobility after arthroscopy in patients with ACL reconstruction, and relieve their knee joint discomfort.