Abstract: Objective To observe the effect of nursing intervention of fast track surgery(FTS)on the recovery of patients with femoral neck fracture after total hip replacement(THA). Methods A total of 150 patients with femoral neck fracture who received total hip arthroplasty were randomly divided into control group and FTS group, with 75 cases in each group. The control group received conventional perioperative care, while the FTS group carried out nursing intervention based on the FTS concept, and the patients were followed up in and out of the hospital for 3 months after the operation. Visual Analogue Scale(VAS)score was used to observe the pain condition of the two groups after operation, and the activity time to first get out of bed, hospitalization time, complication rate and Harris score of hip joint function were recorded. Results The VAS scores at 7 days, 1 month and 3 months after surgery in both groups were significantly lower than those before surgery(P<0.05), and the above scores in the FTS group were significantly lower than those in the control group(P<0.05); the first activity time to get out of bed and hospital stay time in the FTS group were shorter than those in the control group, and the complication rate was 2.67%, which was significantly lower than 12.00% in the control group(P<0.05). Harris scores were significantly improved at 1 month, 2 months and 3 months after surgery in both groups(P<0.05), and the scores of the FTS group were significantly higher than those of the control group(P<0.05). Conclusion FTS nursing intervention applied to patients with femoral and tibial fractures treated by THA can effectively reduce postoperative pain, reduce the occurrence of complications, shorten first activity time to get out of bed and hospital stay of patients, and promote the recovery of hip joint function.