Objective  To explore the safety and effectiveness of the concept of enhanced recovery after surgery (ERAS) applied to the perioperative management of patients undergoing laparoscopic partial nephrectomy.

  Methods  A total of 105 patients with laparoscopic partial nephrectomy were divided into ERAS group (n=55) and control group (n=50). The conventional perioperative protocol was used in the control group, and the ERAS protocol was used in the ERAS group. The postoperative recovery, stress indexes and incidence of complications were compared between the two groups, and the unexpected readmission rate at one month after surgery was compared during follow-up.

  Results  After operation, the first time of drinking water, first time of ventilation, first time of getting out of bed, indwelling time of drainage tube, indwelling time of urinary tube and postoperative hospitalization time in the ERAS group were significantly shorter than those in control group (P < 0.05). The 24 hours postoperative pain score of the ERAS group was significantly lower than that of the control group (P < 0.05). Serum white blood cell count (WBC) at the 3rd day after surgery and C-reactive protein (CRP) levels at the 3rd and 5th day after surgery of the ERAS group were significantly lower than those of the control group (P < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P>0.05).

  Conclusion  ERAS is safe for perioperative management of patients undergoing laparoscopic partial nephrectomy. At the same time, it can relieve postoperative stress reaction and promote early postoperative recovery.