Objective  To compare effects of different angiographic types on in-stent restenosis (ISR) of middle cerebral artery.

  Methods  A total of 116 patients who underwent middle cerebral artery stenting were selected as study objects, and were divided into different types according to location-morphology-pathway (LMA classification), including seven subtypes according to location classification, three subtypes according to morphological classification, and three subtypes according to pathway classification. The restenosis conditions of patients were followed up and the influencing factors of LMA classification of middle cerebral artery ISR were analyzed.

  Results  A total of 116 stents were placed in 116 patients, among whom 18 restenosis cases in recheck results of follow-up were included in restenosis group, and 98 cases without restenosis were included in non-restenosis group. There was no significant difference between the two groups in location types (P>0.05). Significant differences were found in morphology type and pathway type (P < 0.05). The results of univariate analysis showed that the morphological and pathway classification of intracranial artery LMA classification were the influencing factors of postoperative ISR in patients with atherosclerotic middle cerebral artery stenosis.

  Conclusion  The morphological and pathway classification of intracranial artery LMA classification are the influencing factors of postoperative middle cerebral artery ISR, while location classification is not its influencing factor. The incidence rates of ISR with morphological type A and type B as well as pathway type Ⅰ and type Ⅱ are lower, and these patients have better prognosis. For patients with morphological type C and pathway classification Ⅲ, other surgery or conservative treatment may be considered.