Abstract: Objective To analyze the value of computed tomography angiography(CTA)in evaluating carotid artery stenosis and collateral circulation in patients with acute cerebral infarction. Methods A retrospective study was performed to retrospectively analyze the CTA materials of 101 cases with acute cerebral infarction(ACI). Taking Digital Subtraction Angiography(DSA)as gold standard, diagnostic consistency and assessment value of CTA in carotid artery stenosis and collateral circulation in patients with ACI were analyzed, and diagnosis efficiency indexes were calculated. Results The results of CTA in evaluation of carotid artery conditions(normality or occlusion)by CTA were highly consistent with the gold standard, with higher consistency ［Kappa>0.8~1.0, area under the curve(AUC)>0.9, P<0.01］. The results of CTA in evaluation of mild, moderate and severe carotid artery stenosis were moderately consistent with the gold standard, with medium consistency(Kappa>0.6~0.8, AUC>0.7~0.9, P<0.01). The result of CTA in evaluation of collateral circulation was highly consistent with the gold standard, with higher value(Kappa>0.8~1.0, AUC>0.9, P<0.01). Conclusion CTA has a higher value in evaluating the degree of carotid stenosis and collateral circulation in patients with acute cerebral infarction.