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左卡尼汀联合营养素治疗特发性弱畸精子症男性不育的疗效评价

郭廷超, 孟令波, 卢永平, 梁悦

郭廷超, 孟令波, 卢永平, 梁悦. 左卡尼汀联合营养素治疗特发性弱畸精子症男性不育的疗效评价[J]. 实用临床医药杂志, 2020, 24(9): 84-86. DOI: 10.7619/jcmp.202009024
引用本文: 郭廷超, 孟令波, 卢永平, 梁悦. 左卡尼汀联合营养素治疗特发性弱畸精子症男性不育的疗效评价[J]. 实用临床医药杂志, 2020, 24(9): 84-86. DOI: 10.7619/jcmp.202009024
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GUO Tingchao, MENG Lingbo, LU Yongping, LIANG Yue. Evaluation on efficacy of levocarnitine combined with nutrient therapy in the treatment of idiopathic asthenospermia in males with infertility[J]. Journal of Clinical Medicine in Practice, 2020, 24(9): 84-86. DOI: 10.7619/jcmp.202009024
Citation: GUO Tingchao, MENG Lingbo, LU Yongping, LIANG Yue. Evaluation on efficacy of levocarnitine combined with nutrient therapy in the treatment of idiopathic asthenospermia in males with infertility[J]. Journal of Clinical Medicine in Practice, 2020, 24(9): 84-86. DOI: 10.7619/jcmp.202009024
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左卡尼汀联合营养素治疗特发性弱畸精子症男性不育的疗效评价

  • 1. 中国医科大学附属生殖医院 男科, 辽宁 沈阳, 110031;

  • 2. 中国医科大学 国家卫健委生殖健康与遗传医学重点实验室, 辽宁 沈阳, 110031;

  • 3. 中国医科大学附属生殖医院 检验科, 辽宁 沈阳, 110031

详细信息
    通讯作者:

    梁悦,E-mail:85583960@qq.com

  • 中图分类号: R698

Evaluation on efficacy of levocarnitine combined with nutrient therapy in the treatment of idiopathic asthenospermia in males with infertility

  • 1. Department of Andrology, Reproductive Hospital Affiliated to China Medical University, Shenyang, Liaoning, 110031;

  • 2. Key Laboratory of Reproductive Health and Genetic Medicine of National Health Commission, China Medical University, Shenyang, Liaoning, 110031;

  • 3. Department of Laboratory, Reproductive Hospital Affiliated to China Medical University, Shenyang, Liaoning, 110031

摘要

    摘要
  • 摘要: 目的 探讨左卡尼汀联合营养素治疗特发性弱畸精子症男性不育的疗效。 方法 选择72例特发性弱畸精子症男性不育患者作为研究对象,按照治疗方案的不同将患者分为观察组与对照组,各36例。对照组采用常规维生素E联合辅酶Q10治疗,观察组采用左卡尼汀联合营养素治疗。观察2组患者治疗3个月后的各项精液参数,对临床疗效进行综合评价。 结果 治疗后, 2组患者精液量、精子浓度、精子活力、精子DNA完整率以及正常形态精子率均优于治疗前,且观察组患者以上各指标优于对照组,差异均有统计学意义(P<0.05)。 结论 左卡尼汀联合营养素治疗特发性弱畸精子症男性不育疗效可靠,能显著改善患者精液质量。
    Abstract: Objective To investigate the efficacy of levocarnitine combined with nutrient therapy in the treatment of idiopathic asthenospermia in males with infertility. Methods A total of 72 infertility males with idiopathic asthenospermia were recruited as study objects, and were divided into observation group and control group according to different treatment plans, with 36 cases in each group. The control group was treated with routine vitamin E and coenzyme Q10, and the observation group was treated with levocarnitine combined with nutrient therapy. The semen parameters of two groups were observed after 3 months of treatment, and the clinical efficacy was comprehensively evaluated. Results After treatment, semen volume, sperm concentration, sperm motility, sperm DNA integrity rate and normal morphology sperm rate in the two groups were better than pre-treatment, and the above indicators in the observation group were significantly better than those in the control group(P<0.05). Conclusion Combination of levocarnitine and nutrient therapy in the treatment of infertility men with idiopathic asthenozoospermia has reliable efficacy and can significantly improve the quality of semen.
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  • 杜海胜, 王琰, 王新龙, 等. 男性不育患者精子DNA碎片化率与精液常规参数的相关分析[J]. 检验医学与临床, 2018, 15(A01): 141-142.
    常琰. 男性不育患者精子质量与精浆弹性蛋白酶的相关性分析[J]. 中国医药指南, 2019, 17(27): 159-160.
    秦红平, 李亚丽, 李伟文, 等. 显微镜下精索静脉结扎术联合药物对改善少弱畸精子症患者精液质量的初步观察[J]. 生殖医学杂志, 2019, 28(8): 951-954.
    陈翠翠, 虞小芳, 李召东. 男性不育患者生殖激素水平与精子质量的相关分析[J]. 生殖医学杂志, 2018, 27(2): 130-133.
    赵军, 肖舟, 刘洁, 等. 中西药联合治疗特发性少弱畸精子症的有效性和安全性[J]. 深圳中西医结合杂志, 2019, 29(8): 1-3.
    李韬, 谢胜, 谭艳, 等. 麒麟丸联合枸橼酸他莫昔芬片治疗特发性少弱畸精子症的临床疗效观察[J]. 中国性科学, 2018, 27(4): 28-30.

    Adewoyin M, Ibrahim M, Roszaman R, et al. Male infertility: the effect of natural antioxidants and phytocompounds on seminal oxidative stress[J]. Diseases, 2017, 5(1): E9.
    邓敏, 赵洪福. 男性不育症患者促黄体生成素、抗精子抗体指标水平及其与精子前向运动的相关性分析[J]. 标记免疫分析与临床, 2019, 26(4): 650-653.
    黄永祥, 黄丽娜, 刘浩. 左卡尼汀复合营养素治疗特发性弱畸精子症男性不育的临床效果观察[J]. 临床合理用药杂志, 2019, 12(17): 80-81.
    陈永艳, 杜生荣, 林峰, 等. 海马巴戟胶囊与左卡尼汀口服液治疗特发性少弱精子症的疗效比较[J]. 基层医学论坛, 2017, 21(23): 3074-3075.
    陈亮, 张宏斌, 彭爱琴, 等. 麒麟丸联合左卡尼汀治疗特发性少弱精子症的临床观察[J]. 中外医学研究, 2019, 17(10): 43-44.
    张春和, 赵凡, 李焱风, 等. 左卡尼汀口服液联合黄地助育汤治疗少弱精症男性不育的临床研究[J]. 中华中医药学刊, 2017, 35(11): 2735-2737.
    冯科, 夏彦清, 冯宗刚, 等. 左旋肉碱复合营养素治疗弱精子症疗效分析[J]. 中国男科学杂志, 2018, 32(2): 48-51.

    Hao S, Hu J F, Song S Q, et al. Selenium alleviates aflatoxin B1-induced immune toxicity through improving glutathione peroxidase 1 and selenoprotein S expression in primary porcine splenocytes[J]. J Agric Food Chem, 2016, 64(6): 1385-1393.
    黄昌平, 骆强翔, 廖勇彬. 左卡尼汀复合营养素治疗特发性弱畸精子症男性不育患者临床疗效观察[J]. 生殖医学杂志, 2018, 27(6): 545-550.
    周晓皮, 刘军明, 张励, 等. 左卡尼汀对精索静脉曲张男性不育患者术后精液参数影响分析[J]. 现代诊断与治疗, 2018, 29(15): 2483-2484.
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出版历程
  • 收稿日期:  2020-01-11
  • 网络出版日期:  2020-08-27

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