Observation on therapeutic efficacy of moxibustion on umbilicus and Qiwei Baizhu Powder on diarrheal irritable bowel syndrome differentiated as spleen deficiency and dampness
-
摘要:目的 观察灸脐联合七味白术散治疗脾虚湿盛型腹泻型肠易激综合征（IBS-D）的临床效果。方法 选取符合诊断及纳入标准的脾虚湿盛型IBS-D患者60例，按随机法分为观察组与对照组，每组30例。观察组采用灸脐联合七味白术散治疗，对照组采用匹维溴铵治疗。治疗4周为1个疗程。治疗前后分别评估IBS-D中医证候积分，治疗结束后第1、2、3个月对患者进行随访，观察患者复发情况。结果 治疗后，2组腹泻、肠鸣、腹痛等症状均有所改善，观察组IBS-D中医证候积分低于对照组，差异有统计学意义（P < 0.05）。观察组治疗总有效率为90.00%，高于对照组的43.33%，差异有统计学意义（P < 0.05）。观察组复发率低于对照组，差异有统计学意义（P < 0.05）。结论 治疗脾虚湿盛型IBS-D患者，灸脐联合七味白术散与单纯口服匹维溴铵比较疗效更佳，能有效降低治疗后复发率，缓解患者痛苦。Abstract:Objective To observe the clinical effect of moxibustion on umbilicus and Qiwei Baizhu Powder on diarrheal irritable bowel syndrome(IBS-D)differentiated as spleen deficiency and dampness.Methods A total of 60 patients with IBS-D differentiated as spleen deficiency and dampness who met the diagnosis and inclusion criteria were selected. The observation group was treated with moxibustion and Qiwei Baizhu Powder, and the control group was treated with pinaverium bromide. The treatment lasted for 4 weeks as a course. The TCM syndrome score of IBS-D was evaluated before and after treatment, and the patients were followed up for 1 month, 2 and 3 months after treatment, and the recurrence conditions of these patients were observed.Results After treatment, diarrhea, borborygmus, abdominal pain and other symptoms were improved in both groups, and the TCM syndrome score of IBS-D in the observation group was lower than that in the control group, the differences were statistically significant (P < 0.05). The total effective rate of the observation group was 90.00%, which was significantly higher than 43.33% of the control group (P < 0.05). The recurrence rate of the observation group was significantly lower than that of the control group(P < 0.05).Conclusion Moxibustion on umbilicus and Qiwei Baizhu Powder has better clinical efficacy than simple oral administration of pinaverium bromide in patients with IBS-D differentiated as spleen deficiency and dampness, which can effectively reduce the recurrence rate after treatment, and relieve the pain of IBS-D patients.
-
-
[1] 李君, 马鸣悦, 周洪光, 等. 肠易激综合征的研究进展及未来突破方向[J]. 中华消化病与影像杂志: 电子版, 2020, 10(4): 145-148. doi: 10.3877/cma.j.issn.2095-2015.2020.04.001 [2] 朱诗玮, 王志仁, 段丽萍. 中国肠易激综合征和抑郁症患者具有相同的遗传易感性位点[J]. 中华内科杂志, 2020, 59(5): 391-391. [3] 朱瑞刚. 匹维溴胺联合曲美布丁痛泻宁治疗肠易激综合征的疗效观察[J]. 黑龙江医学, 2020, 44(4): 523-525. doi: 10.3969/j.issn.1004-5775.2020.04.037 [4] 戴宁, 邹多武. 从罗马Ⅳ标准角度分析肠易激综合征的药物治疗现状[J]. 中华消化杂志, 2016, 36(12): 855-857. doi: 10.3760/cma.j.issn.0254-1432.2016.12.017 [5] 吴巧珑, 涂云. 中西医结合治疗腹泻型肠易激综合征的临床研究[J]. 黑龙江中医药, 2020, 49(3): 376-377. https://www.cnki.com.cn/Article/CJFDTOTAL-HLZY202003288.htm [6] 李琳, 江登丰, 张鹏飞, 等. 五音疗法联合痛泻要方加味治疗肝郁脾虚腹泻型肠易激综合征28例临床观察[J]. 湖南中医杂志, 2020, 36(8): 48-50. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZO202008021.htm [7] 林艺, 郑媛媛. IBS典型症状严重程度与血清25-(OH)D水平的相关性研究[J]. 中国医学创新, 2020, 17(21): 116-119. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYCX202021033.htm [8] 杨芳, 严晶, 刘丽娜, 等. 肠易激综合征病因及发病机制研究的新进展[J]. 河北医科大学学报, 2020, 41(8): 987-992. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYX202008027.htm [9] 蔡骊骊, 郭传勇, 钱静蓉, 等. 匹维溴铵联合乳果糖在肠道准备中的应用[J]. 中国中西医结合消化杂志, 2020, 28(1): 23-27. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXPW202001007.htm [10] 郭抗萧, 彭昕欣, 毛娅男, 等. 七味白术散对菌群失调腹泻小鼠肠道蔗糖酶活性的影响[J]. 中国微生态学杂志, 2019, 31(10): 1130-1134. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGWS201910003.htm [11] 顾思浩, 孔维崧, 张彤, 等. 白术的化学成分与药理作用及复方临床应用进展[J]. 中华中医药学刊, 2020, 38(1): 69-73. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202001017.htm [12] 张新普, 温友禄, 徐海燕, 等. 壮灸神阙穴治疗阳虚质抑郁症的疗效观察[J]. 时珍国医国药, 2019, 30(11): 2690-2692. https://www.cnki.com.cn/Article/CJFDTOTAL-SZGY201911043.htm -
期刊类型引用(1)
1. 刘钟城，龙美春，肖志明，郭勤. 原发性小肠肿瘤临床特征分析. 医学信息. 2021(18): 122-125 . 
百度学术
其他类型引用(0)
计量
- 文章访问数: 418
- HTML全文浏览量: 240
- PDF下载量: 11
- 被引次数: 1
下载:
苏公网安备 32100302010246号