Effects of different oxygen inhalation methods on reintubation rate and oxygenation index of ICU patients after weaning
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摘要: 目的 探讨ICU患者撤机后不同吸氧方式对患者再次插管率和氧合指数的影响。 方法 选取122例ICU内气管插管行机械通气的患者作为研究对象,按照随机数字表法分成研究组和对照组,各61例。对照组患者在撤机后进行常规吸氧,研究组患者进行经鼻高流量吸氧, 2组其他护理和治疗完全相同。观察并比较2组患者氧合指数变化情况以及再插管率情况。 结果 治疗后,研究组的再插管率(6.6%)低于对照组(19.7%), 差异有统计学意义(P<0.05); 治疗后1、8、24 h, 研究组呼吸频率、动脉血二氧化碳分压低于对照组,动脉血氧分压、氧合指数高于对照组,差异均有统计学意义(P<0.05)。 结论 ICU患者撤机后经鼻高流量吸氧可有效降低再插管率,提高氧合指数,是一种有效的新型呼吸支持模式。Abstract: Objective To study the effects of different oxygen inhalation methods on reintubation rate and oxygenation index of ICU patients after weaning. Methods A total of 122 ICU patients with endotracheal intubation who underwent mechanical ventilation were selected as research objects. According to the random number table method, they were randomly divided into study group and control group, with 61 cases in each group. The control group was treated by routine oxygen inhalation after weaning, while the study group was treated by transnasal high-flow oxygen inhalation, and other care and treatments were the same in both groups. The changes in oxygenation index and re-intubation rate of the two groups were observed and compared. Results After treatment, the intubation rate of the study group was significantly lower than that of the control group(6.6% vs. 19.7%, P<0.05). The respiratory frequency and partial carbon dioxide pressure of the study group at 1, 8, and 24 h after treatment were significantly lower than those of the control group, and the arterial oxygen partial pressure and oxygenation index were significantly higher than those of the control group, the differences between the two groups were statistically significant(P<0.05). Conclusion Transnasal high-flow oxygen inhalation after weaning for ICU patients can effectively reduce re-intubation rate and increase the oxygenation index, which is a new and an effective breathing support mode.
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