惊厥性癫痫持续状态患儿相关指标及头颅磁共振成像价值的研究进展

Research progress on values of related indicators and cranial magnetic resonance imaging in children with convulsive status epilepticus

摘要: 惊厥性癫痫持续状态是儿童时期常见的急危重症之一，其发病机制与肿瘤坏死因子-α(TNF-α)、神经元特异性烯醇化酶(NSE)、S100B蛋白(S100B)有着密切的联系。惊厥性癫痫持续状态常伴有颅脑损伤，导致头颅磁共振成像(MRI)改变。本研究对TNF-α、NSE、S100B及头颅MRI在儿童惊厥性癫痫持续状态中价值的研究进展进行综述。

Abstract: Convulsive status epilepticus is one of the most common acute and critical illnesses in childhood, and its pathogenesis is closely related with tumor necrosis factor-α (TNF-α), neuron-specific enolase (NSE) and S100B protein (S100B). Convulsive status epilepticus is often accompanied by craniocerebral injury, which can lead to changes in cranial magnetic resonance imaging (MRI). This study reviewed the research progress on values of TNF-α, NSE, S100B and cranial MRI in children with convulsive status epilepticus.