危重病例评分联合血清D-二聚体、降钙素原对儿童感染病情的评估价值

彭昊, 李德优, 邓敏, 肖晨, 荣建国

彭昊, 李德优, 邓敏, 肖晨, 荣建国. 危重病例评分联合血清D-二聚体、降钙素原对儿童感染病情的评估价值[J]. 实用临床医药杂志, 2020, 24(2): 48-51. DOI: 10.7619/jcmp.202002014
引用本文: 彭昊, 李德优, 邓敏, 肖晨, 荣建国. 危重病例评分联合血清D-二聚体、降钙素原对儿童感染病情的评估价值[J]. 实用临床医药杂志, 2020, 24(2): 48-51. DOI: 10.7619/jcmp.202002014
PENG Hao, LI Deyou, DENG Min, XIAO Chen, RONG Jianguo. Value of critical illness score combined with serum D-dimer and procalcitonin in the evaluation of infection condition in children[J]. Journal of Clinical Medicine in Practice, 2020, 24(2): 48-51. DOI: 10.7619/jcmp.202002014
Citation: PENG Hao, LI Deyou, DENG Min, XIAO Chen, RONG Jianguo. Value of critical illness score combined with serum D-dimer and procalcitonin in the evaluation of infection condition in children[J]. Journal of Clinical Medicine in Practice, 2020, 24(2): 48-51. DOI: 10.7619/jcmp.202002014

危重病例评分联合血清D-二聚体、降钙素原对儿童感染病情的评估价值

详细信息
  • 中图分类号: R720.5

Value of critical illness score combined with serum D-dimer and procalcitonin in the evaluation of infection condition in children

  • 摘要: 目的 探讨危重病例评分联合血清D-二聚体(D-D)、降钙素原(PCT)对儿童感染病情的评估价值。 方法 将102例感染儿童依据感染类型分为病毒感染组29例与细菌感染组73例,根据感染程度分为普通感染组65例与重度感染组37例。选取同期健康儿童96例作为对照组。比较各组儿童危重病例评分、血清D-D及PCT的含量,分析各个指标评估儿童感染病情的价值。 结果 细菌感染组、对照组、病毒感染组的危重病例评分、血清D-D含量、血清PCT含量两两比较,差异均有统计学意义(P<0.05)。重度感染组、普通感染组、对照组的危重病例评分、血清D-D含量、血清PCT含量两两比较,差异均有统计学意义(P<0.05)。危重病例评分、血清D-D、血清PCT联用对儿童感染病情评估的敏感性为90.2%, 特异性为95.8%, 阳性预测值为95.8%, 阴性预测值为90.2%。 结论 危重病例评分联合血清D-D、PCT在儿童感染病情早期评估中具有重要的临床意义。
    Abstract: Objective To explore the value of critical illness score combined with serum D-dimer(D-D)and procalcitonin(PCT)in the evaluation of infection condition in children. Methods Totally 102 infected children were divided into virus infection group(n=29)and bacteria infection group(n=73)according to infection type, and they were also divided into common infection group(n=65)and severe infection group(n=37)according to the degree of infection. At the same time, 96 healthy children were selected as control group. The critical illness score, the contents of serum D-D and PCT were compared between each group, and the value of each index in evaluation of the infection condition in children was analyzed. Results There were significant differences in critical illness score, serum D-D content and serum PCT content between two groups in bacterial infection group, control group and virus infection group(P<0.05). There were significant differences in critical illness score, serum D-D content and serum PCT content between two groups in severe infection group, common infection group and control group(P<0.05). In the evaluation of infection condition by combination of critical illness score, serum D-D and PCT, the sensitivity, specificity, positive predictive value and negative predictive value were 90.2%, 95.8%, 95.8% and 90.2% respectively. Conclusion Critical illness score combined with serum D-D and PCT has an important clinical significance in early evaluation of infection condition in children.
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出版历程
  • 收稿日期:  2019-11-10
  • 网络出版日期:  2020-08-26
  • 发布日期:  2020-08-26

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