Abstract: Objective To explore the effect of Doula instrument combined with Doula accompanying on delivery pain and quality of elderly primiparas. Methods A total of 150 elderly natural delivery primiparas were divided into routine group(n=75)and Doula group(n=75)by computer randomized method. The routine group was given the traditional mode of labor, and the delivery was performed after the opening of the uterine orifice. The Doula group was given the labor analgesia by Doula instrument combined with one-to-one whole-course Doula accompanying. The Visual Analogue Scale(VAS)score, the time of labor, the mode of delivery, the amount of bleeding at 2 hours after delivery and the occurrence of postpartum complications were observed. Results There was no significant difference between the two groups in the third stage of labor(P>0.05). The VAS score of labor pain in the Doula group were(4.23±1.06)points, which was lower than(7.87±1.45)points in the routine group, the first stage of labor, the second stage of labor and whole-course labor time were(383.51±108.31)min,(45.73±8.30)min,(437.07±112.56)min, respectively, in the Doula group, which were shorter than(472.08±125.72),(61.30±10.51),(541.70±138.07)min, respectively, in the routine group. The amount of postpartum hemorrhage was(109.54±28.30)mL, which was lower than(132.34±31.25)mL in the routine group(P<0.05). The natural delivery rate of Doula group was higher than that of the conventional group(93.33% vs. 82.67%), and the cesarean section rate was lower(6.67% vs. 17.33%), the total complication rate of the - Doula group was significantly lower than that of the conventional group(2.67% vs. 12.00%), which all showed significant differences(P<0.05). Conclusion Doula instrument combined with Doula accompanying can significantly reduce the pain of delivery, shorten the labor time, promote natural childbirth, reduce complication rates such as neonatal asphyxia, postpartum infection and urinary retention.