男男性行为史对首诊于呼吸内科的获得性免疫缺陷综合征患者辅检结果的影响

桑琳莉; 唐为安; 杨俊俊; 徐兴祥

doi:10.7619/jcmp.201924013

男男性行为史对首诊于呼吸内科的获得性免疫缺陷综合征患者辅检结果的影响

Influence of male-male sexual behavior historyon supplementary examination results in patients with acquired immunodeficiency syndrome first diagnosed in respiratory department

摘要

摘要:
目的探讨不同性行为史对于以肺部感染症状首诊于呼吸内科的获得性免疫缺陷综合征(AIDS)患者肺部感染常见检验指标以及肺部CT影像检查结果的影响。
方法选取以肺部感染症状就诊并确诊AIDS的51例患者作为研究对象，按不同性行为史分为男男组17例、异性组34例，比较2组患者的氧分压、红细胞沉降率(ESR)、降钙素原(PCT)、C反应蛋白(CRP)指标以及主要临床症状、肺部CT检测影像病变情况。
结果男男组和异性组的咳嗽、发热、胸闷气喘症状相比，差异无统计学意义(P>0.05); 男男组的PCT、ESR与异性组相比，差异无统计学意义(P>0.05); 男男组的CRP水平、双侧肺部影像病变率低于异性组，差异有统计学意义(P < 0.05)。
结论不同的性行为史对于AIDS患者肺部感染常见辅助检查结果具有一定的预测价值，其中男男性行为史患者的全身炎症反应程度较异性性行为史患者低，且单侧肺部病变率相对更高，本研究结果对于丰富AIDS患者的肺部感染治疗方案具有较高的借鉴价值。

Abstract:
Objective To investigate the effect of different sexual behaviors on indicators of pulmonary infection and pulmonary CT imaging for Acquired Immunodeficiency Syndrome (AIDS) patients firstly diagnosed by respiratory symptoms.
Methods A total of 51 patients visiting the doctors for pulmonary symptoms and confirmed as AIDS in our hospital were selected in the study, and were divided into male-male sexual behavior group(n=17) and male-female sexual behavior group(n=34) according to the differed sexual behavioral histories. The oxygen partial pressure, erythrocyte sedimentation rate(ESR), procalcitonin(PCT), C reactive protein(CRP), main clinical symptoms and lung lesions by CT imaging were compared between the two groups.
Results The symptoms such as cough, fever, chest tightness, and PCT and ESR levels showed no statistically significant differences in male-male sexual behavior group and male-female sexual behavior group(P>0.05), while the CRP level and rate of lateral lung lesion in the male-male sexual behavior group than that in lower male-female sexual behavior group (P < 0.05).
Conclusion Different history of sexual behaviors has certain predictive value for supplementary examination for lung infection. Male patients with homosexual behaviors have a lower incidence of systemic inflammatory infection, and more likely occur a higher incidence of unilateral lung lesions, which is of great significance in further enriching the lung treatments of AIDS patients.

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