超声引导下肌肉骨骼软组织肿块芯针穿刺活检与术后病理检查结果的一致性分析

Analysis of consistency between core needle biopsy of musculoskeletal or soft tissue mass under guidance of ultrasound and postoperative pathological examination results

  • 摘要:
      目的  探讨超声引导下肌肉骨骼软组织肿块芯针穿刺活检(CNB)与术后病理检查结果的一致性及临床意义。
      方法  选取66例因肌肉骨骼软组织肿块行CNB并行手术切除的患者作为研究对象,采用Kappa检验分析CNB病理与手术病理结果的一致性。
      结果  本组穿刺成功率100.0%, CNB病理正确率72.7%(48/66)、支持率19.7%(13/66)、阴性率7.6%(5/66)、总有效率92.4%(61/66); CNB病理及手术病理具有强一致性(κ=0.909, P < 0.001); 89.2%(33/37)良性患者和96.6%(28/29)恶性患者的CNB病理支持或完全符合手术病理。
      结论  肌肉骨骼软组织肿块的CNB病理与手术病理一致性较好,可为术前准备及术式选择提供良好的依据。

     

    Abstract:
      Objective  To investigate the consistency and clinical significance of ultrasound-guided core needle biopsy(CNB) for patients with musculoskeletal or soft tissue masses and postoperative pathological examination results.
      Methods  A total of 66 patients with musculoskeletal or soft tissue masses who underwent CNB and surgical resection of the lesions were collected. The consistency of CNB and surgical pathological examination was determined using Kappa test.
      Results  The success rate of puncture in all 66 patients was 100.0%. The pathological accuracy rate, support rate, negative rate and total effective rate of CNB under ultrasound guidance were 72.7%(48/66), 19.7%(13/66), 7.6%(5/66) and 92.4%(61/66), respectively. There was a strong consistency between CNB pathology and surgical pathology (κ=0.909, P < 0.001). CNB pathological results showed that 89.2%(33/37)benign patients and 96.6%(28/29) patients confirmed as malignant tumors were almost in accordance with surgical pathological results.
      Conclusion  The ultrasound-guided CNB pathological diagnosis for muscle, bone and soft tissue masses has better agreement with the pathological diagnosis of surgical specimens, and provides a good basis for the preparation and choice of operation modes.

     

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