Objective  To investigate the effect of whole-course epidural labor analgesia on coagulation function in vaginal delivery in women with hypertensive pregnancy.

  Methods  A total of 100 cases with gestational hypertension in department of obstetrics and gynecology were included in the study. They were divided into two groups according to different analgesia methods. The natural delivery puerperae in control group(n=50) were given no analgesic treatment, while those in observation group(n=50) was performed epidural labor analgesia during vaginal delivery. The blood coagulation function of the two groups was compared.

  Results  Compared with the control group, the prothrombin time (PT) and activated partial thromboplastin time(APTT) were significantly longer in the observation group, and the D-dimmer(DD) and fibrinogen(FIB) were significantly decreased (P < 0.05). The nursing satisfaction in the observation group was significantly higher than that of the control group (94.00% vs. 80.00%, P < 0.05).

  Conclusion  For pregnant women with hypertensive hypertension, the application of full-course epidural labor analgesia can significantly improve the hypercoagulable state of blood and increase the safety of vaginal delivery in pregnant women with hypertension.