Objective  To compare the effect of Vitallium2000 casting denture, pure titanium denture and cobalt chromium alloy denture in denture restoration.

  Methods  Totally 150 patients with denture restoration were divided into Vitallium 2000 group, pure titanium group and the cobalt-chromium group according to the scaffold materials. The results of restoration, masticatory efficiency and satisfaction degree were compared among the three groups.

  Results  The incidence rates of oral mucosal inflammation at 1 and 2 years after treatment was 0 and 2.00% in Vitalium 2000 group, which were significantly lower than those in pure titanium group (12.00%, 16.00%) and cobalt-chromium alloy group (22.00%, 32.00%) (P < 0.05). The masticatory efficiency of Vitalum 2000 group at 1 and 2 years after treatment was significantly higher than that of pure titanium group and cobalt-chromium alloy group (P < 0.05). The satisfactory degree of denture restoration in Vitallium 2000 group was 96.00%, which was significantly higher than 76.0% in pure titanium group and 70.00% in cobalt-chromium alloy group (P < 0.05). The retention force in 1 and 2 years after treatment in Vitallium 2000 group was significantly higher than that in pure titanium group and cobalt-chromium alloy group (P < 0.05).

  Conclusion  Compared with cobalt-chromium alloy denture and titanium denture, Vitallium 2000 casting denture has the advantages of high strength, stability and good aesthetics, which can maintain the ideal retention force for a long time.