冠状动脉CT血管造影在冠心病患者斑块定量评估及预后评估中的应用价值

Value of coronary CT angiography in quantitative assessment and prognostic assessment of plaque in patients with coronary heart disease

  • 摘要:
      目的  研究冠状动脉CT血管造影(CTA)在冠心病患者斑块定量及预后评估中的应用价值。
      方法  收集本院接诊的60例临床疑似冠状动脉病变患者的临床资料。以CAG结果为参照, 评价CTA管腔狭窄程度诊断的准确性; 以冠状动脉造影(CAG)为金标准,评价CTA的诊断效能。
      结果  冠状动脉CTA检测所得的轻中重度患者的病理参数与CGA检查结果相比,差异无统计学意义(P>0.05)。CTA在诊断轻中重度狭窄的灵敏度分别为73.69%、80.42%、87.77%, 特异性为95.63%、96.82%、97.14%。心肌缺血组钙化积分、斑块负荷、狭窄程度以及重建指数均显著优于无心肌缺血组(P < 0.05)。心肌缺血组钙斑块体积与无心肌缺血组差异无统计学意义(P>0.05)。
      结论  冠状动脉CTA在冠心病患者斑块定量评估及预后评估中的有较高的应用价值。

     

    Abstract:
      Objective  To study the value of coronary computed tomography angiography (CTA) in quantitative assessment and prognosis assessment of plaque in patients with coronary heart disease.
      Methods  The clinical data of 60 patients with suspected coronary artery disease were collected. According to the results of coronary arteriography(CAG), the diagnostic accuracy of stenosis degree by Computed Tomography Angiography(CTA) was compared and evaluated, and the diagnostic efficacy of CTA was evaluated taking CAG as golden standard.
      Results  There were no significant difference in the pathological indicators of mild, moderate and severe patients detected by CTA compared with the results of CGA (P>0.05). The sensitivity of CTA in the diagnosis of mild, moderate and severe stenosis were 73.69%, 80.42%, 87.77%, and specificity were 95.63%, 96.82% and 97.14%, respectively. The calcification scores, plaque load, stenosis degree and reconstruction index of myocardial ischemia group were significantly better than those of non-myocardial ischemia group (P < 0.05). There was no significant difference in the volume of calcium plaque between myocardial ischemia group and non-myocardial ischemia group (P>0.05).
      Conclusion  CTA for coronary artery is of great value in the quantitative assessment of plaque and prognosis in patients with coronary heart disease.

     

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