Objective  To analyze the risk factors of postoperative hormone-induced intraocular hypertension in patients with cataract surgery.

  Methods  A retrospective analysis was performed on clinical data of 792 cases (792 eyes) who underwent phacoemulsification combined with intraocular lens implantation in our hospital. According to the occurrence of postoperative hormone-induced intraocular hypertension, they were divided into hormone-induced intraocular hypertension group and non-hormone-induced intraocular hypertension group. The gender, age, cataract crystal nucleus classification, high myopia, hypertension, diabetes mellitus, preoperative complicating with glaucoma, preoperative complicating with uveitis, preoperative ocular trauma and intraoperative complications were compared between the two groups. Multivariate Logistic regression analysis was used to evaluate the risk factors for steroid-induced intraocular hypertension after phacoemulsification and intraocular lens implantation.

  Results  Out of 792 patients, 29 cases (3.66%) with hormone-induced intraocular hypertension were included in hormone-induced intraocular hypertension group, and 763 cases (96.34%) without hormone-induced intraocular hypertension were included in non-hormone-induced intraocular hypertension group. There were no significant differences in the gender, cataract crystal nucleus classification, hypertension, preoperative complicating with glaucoma between the two groups (P>0.05). The age in hormone-induced intraocular hypertension group was lower than that in non-hormone-induced intraocular hypertension group (P < 0.05), and the incidence of high myopia, diabetes mellitus, preoperative complicating with uveitis, preoperative complicating with ocular trauma and intraoperative complications in hormone-induced intraocular hypertension group were higher than those in non-hormone-induced intraocular hypertension group (P < 0.05 or P < 0.01). Logistic regression analysis showed that elder age was an independent protective factor affecting hormone-induced intraocular hypertension group after phacoemulsification combined with intraocular lens implantation (OR=0.660, P < 0.05), and high myopia, diabetes mellitus, preoperative complicating with uveitis, preoperative complicating with ocular trauma and intraoperative complications were independent risk factors (OR=1.893, 1.669, 2.487, 2.069, 2.568, P < 0.05 or P < 0.01).

  Conclusion  The young patients with cataract surgery and those with high myopia, diabetes mellitus, uveitis, ocular trauma and intraoperative complications are prone to occurring postoperative hormone-induced intraocular hypertension. Clinically, targeted prevention and control measures should be taken to improve the prognosis of cataract patients.