消化内镜下氩离子凝固术治疗胃十二指肠出血的疗效研究

Efficiency of argon plasma coagulation under digestive endoscope treatment of gastroduodenal hemorrhage

  • 摘要:
      目的  探讨消化内镜下氩离子凝固术(APC)治疗胃十二指肠出血的疗效。
      方法  选取70例胃十二指肠出血患者作为研究对象,根据手术方法的不同将患者分为对照组、观察组,各35例。对照组采用消化内镜下注射治疗,观察组采用消化内镜下APC治疗,比较2组患者治疗后的疗效、住院时间、输血量、出血量、止血时间及并发症发生率。
      结果  观察组的治疗总有效率为97.14%, 显著高于对照组的80.00%(P < 0.05); 观察组的住院时间(5.45±0.64) d、止血时间(1.77±0.20) d显著短于对照组的住院时间(8.95±0.82) d、止血时间(3.20±0.46) d(P < 0.05); 观察组的输血量(423.16±45.61) mL、出血量(388.68±42.44) mL显著少于对照组的输血量(804.28±86.90) mL、出血量(521.52±57.14) mL(P < 0.05); 观察组的并发症发生率为5.71%, 显著低于对照组的25.71%(P < 0.05)。
      结论  消化内镜下APC治疗胃十二指肠出血的疗效显著,能迅速有效止血,减少并发症的发生。

     

    Abstract:
      Objective  To explore the effect of argon plasma coagulation (APC) under digestive endoscope in treatment of gastroduodenal hemorrhage.
      Methods  Totally 70 patients with gastroduodenal hemorrhage were selected. According to surgical methods, the patients were divided into control group and observation group, with 35 cases in each group. The control group was treated by injection under digestive endoscope, while the observation group was treated by APC under digestive endoscope. The curative effect, hospitalization time, blood transfusion volume, bleeding volume, hemostasis time and the incidence rate of complications were compared between two groups.
      Results  The total effective rate of the observation group was 97.14%, which was significantly higher than 80.00% of the control group (P < 0.05). The hospitalization time and hemostasis time of the observation group were (5.45±0.64) days and (1.77±0.20) days, which were significantly shorter than (8.95±0.82) days and (3.20±0.46) days of the control group (P < 0.05). The blood transfusion volume and the amount of blood transfusion in the observation group were (423.16±45.61) mL and (388.68±42.44) mL, which were significantly less than (804.28±86.90) mL and (521.52±57.14) mL in the control group (P < 0.05). The incidence rate of complications in the observation group was 5.71%, which was significantly lower than 25.71% in the control group (P < 0.05).
      Conclusion  APC under digestive endoscopy is effective in treatment of gastroduodenal hemorrhage, which can stop bleeding quickly and reduce incidence of complications.

     

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