Objective  To investigate the clinical characteristics and prognostic factors of very low birth weight (VLBW) in our hospital.

  Methods  The clinical data of 120 VLBW neonates admitted to our hospital were reviewed. The clinical characteristics of neonates with VLBW, maternal perioperative basic information, and the incidence of complications of neonates were analyzed, the prognostic factors of the VLBW neonates were summarized.

  Results  The gestational age and birth weight of neonates in the unhealed group were significantly lower than those in the cured group(P < 0.05), and the length of hospital stay was shorter than that in the cured group(P < 0.05). There were no significant differences in dilivery age, and the ratios of gestational diabetes mellitus and habitual abortion(P>0.05). The proportion of mothers with higher child-bearing age in the unhealed group was significantly higher than that in the cured group(P < 0.05), and there was significant difference in ratio of gestational diabetes between two groups(P < 0.05). The incidences of complications such as respiratory failure, hyperlactacidemia and hypoglycemia in the cured group was significantly lower than that in the unhealed group(P < 0.05).

  Conclusion  The VLBW infants affecting by many factors have higher mortality. Therefore, reasonable management and treatment programs should be developed according to these factors in clinical practice, so as to improve the survival rate and quality of life of VLBW infants.