Objective  To analyze the influence of different timing of umbilical vein catheterization and its clinical effect during neonatal critical care treatment.

  Methods  A total of 80 neonatal critically ill neonates admitted to our hospital were divided into two groups according to different timing of umbilical vein catheterization. The neonates in experimental group received umbilical vein catheterization within 30 minutes after birth, those in the control group received umbilical vein catheterization at 2 to 6 hours after birth. The therapeutic effects, incidence of complications, mean indwelling time, success rate of catheterization, and the number of cases with indwelling time over one week were compared between the two groups.

  Results  The effective rate of treatment and the success rate of catheterization in the experimental group were higher than those in the control group (P < 0.05). The average indwelling time of the experimental group was lower than that of the control group (P < 0.05). The proportion of neonates with retention time more than 1 week and the incidence of complications of the experimental group were lower than that in the control group (P < 0.05).

  Conclusion  Umbilical vein catheterization can effectively improve the clinical efficacy, effectively shorten the indwelling time, and has higher success rate of catheterization during the rescue of neonates.