Abstract:
Objective To investigate the value of microcirculation resistance index (IMR) in evaluating prognosis of patients with acute anterior ST-segment elevation myocardial infarction (STEMI) after emergency percutaneous coronary intervention (PCI) and related influencing factors.
Methods Totally 50 patients with acute anterior STEMI by PCI were selected, and IMR was measured immediately after PCI. Taking IMR=40 U as the cutoff value, patients with IMR < 40 U was defined as normal microcirculation group (group A), and those with IMR≥40 U was defined as abnormal microcirculation group (group B). The general data, laboratory results, intraoperative information, and echocardiographic results at 24 hours, 6 months and 12 months after operation were analyzed. Major adverse cardiac events (MACE) at 12 months after operation were analyzed.
Results Logistic regression analysis showed that time from onset of symptoms to balloon dilation (STB) was an independent risk factor for microcirculation disorders in acute anterior STEMI patients. At 24 hours, 6 months and 12 months after PCI, there were significant differences in the left ventricular ejection fraction (LVEF) and left ventricular end-diastolic volume diameter (LVEDD) between the two groups (P < 0.05). There was a significant difference in MACE between the two groups (P < 0.05).
Conclusion STB is an independent risk factor for microcirculation disorders in acute anterior STEMI patients. IMR may have a good early predictive value for left ventricular remodeling, recovery of left cardiac function and incidence of MACE after PCI in acute anterior STEMI patients.
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