蔗糖铁注射液治疗上消化道出血合并缺铁性贫血的临床疗效

Clinical efficacy of iron sucrose for injection in treatment of iron deficiency anemia patients with upper gastrointestinal hemorrhage

  • 摘要:
      目的  探讨上消化道出血患者缺铁性贫血应用蔗糖铁注射液治疗的临床疗效。
      方法  选取80例上消化道出血合并缺铁性贫血患者作为研究对象, 均采用药物治疗,将采取琥珀酸亚铁片治疗的40例患者设为对照组,将采取蔗糖铁注射液治疗的40例患者设为研究组,比较2组患者整体疗效、纠正贫血所耗时间的差异。
      结果  研究组患者整体治疗有效率为95.00%, 显著高于对照组的77.50%(P < 0.05); 研究组患者平均纠正贫血所耗时间为(17.66±3.63) d, 显著短于对照组的(21.62±4.18)d(P < 0.05); 治疗前, 2组患者平均血红蛋白指标水平无显著差异(P>0.05); 治疗后, 2组患者血红蛋白指标水平均显著高于治疗前(P < 0.05), 且研究组显著高于对照组(P < 0.05)。
      结论  应用蔗糖铁注射液治疗上消化道出血患者的缺铁性贫血,可快速纠正患者贫血症状,并恢复其血红蛋白等指标。

     

    Abstract:
      Objective  To investigate the clinical effect of iron sucrose injection in the treatment of iron deficiency anemia patients with upper gastrointestinal hemorrhage.
      Methods  A total of 80 patients with upper gastrointestinal hemorrhage complicated with iron deficiency anemia were selected in our hospital, given medical treatment. The patients treated with Ferrous Succinate Tablets were selected as control group (n=40) and those treated with ferrous sucrose injection were as study group (n=40). The overall curative effect and time in rectification of iron deficiency anemia the two groups were compared.
      Results  The overall effective rate of treatment in the study group was higher than that in the control group (95.00% vs. 77.50%, P < 0.05). The average time of anemia correction in the study group was (17.66±3.63) days, which was shorter than (21.62±4.18) day in the control group (P < 0.05). Before treatment, the average hemoglobin of the two groups showed no significant difference (P>0.05), and was higher after treatment than before treatment in two groups(P < 0.05), and the study group was higher than the control group (P < 0.05).
      Conclusion  Iron deficiency anemia in patients with upper gastrointestinal hemorrhage can be treated with iron sucrose injection, which can quickly correct the symptoms of anemia and restore their hemoglobin indicators.

     

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