Objective  To investigate the efficacy and adverse reactions of ultrasound-guided injection of lauromacrogol in the treatment of hepatorenal cyst.

  Methods  A total of 68 patients (69 cysts) with hepatorenal cyst were treated with sclerotherapy by ultrasound-guided injection of lauromacrogol. Changes in cyst volume and its efficacy during follow-up at 1, 3, and 6 months after surgery were observed.

  Results  All the 68 patients were successfully punctured, and all the cysts were reduced by more than 50% after 1 month. A total of 27 cysts disappeared after 3 months of treatment, and 65 disappeared or nearly disappeared after 6 months. The effective rate was 100.0% and the cure rate was 94.2%. There were no obvious adverse reactions in 63 patients. Out of the rest 5 patients, mild burning sensation occurred in 3 patients and low postoperative fever in 2 patients.

  Conclusion  Lauromacrogol, as a new type of hardeners for hepatorenal cyst, had significantly lower adverse reactions, better cure rate and definite curative efficacy.