Objective  To investigate the clinical etiology of fever patients with type 2 diabetes mellitus.

  Methods  A total of 46 patients with type 2 diabetes mellitus complicated with fever were selected in Qixia District Hospital of Nanjing City. The causes of fever, and the relationship between fever and glycosylated hemoglobin, white blood cells, hypersensitive C-reactive protein (hs-CRP), total protein were analyzed.

  Results  Of 46 patients, 44 cases (91.30%) were definitely diagnosed, and the rest 2 (4.35%) were malignant tumors. Glycosylated hemoglobin, leukocyte hypersensitive C-reactive protein (hs-CRP), total protein in patients who suffered from diabetes mellitus ≥ 10 years and those within 10 years showed no differences, and the time of anti-infection was not significantly prolonged. Compared with other infections, the glycosylated hemoglobin and hs-CRP were significantly increased in patients with pyogenic infection of the deep organs, and the time of anti-infection was significantly prolonged(P < 0.05). There were no significant differences in white blood cells and total protein(P>0.05).

  Conclusion  Infectious diseases are the main cause of fever in diabetic patients. Glycosylated hemoglobin, leukocyte, hs-CRP, total protein and anti-infection time have no correlation with the course of diabetes mellitus.