高级检索

红玉赔赈颗粒对脓毒症气分证患者炎症指标的干预效果

Effect of Hongyu Peizhen Granule on inflammatory indicators in sepsis patients differentiated as pathogen involving Qifen

    摘要
  • 摘要:
      目的  探讨红玉赔赈颗粒对脓毒症患者血白细胞计数(WBC)、中性粒细胞百分比(N%)、超敏C反应蛋白(hs-CRP)、红细胞沉降率(ESR)、血清降钙素原(PCT)、动脉血乳酸(Lac)炎症指标的干预作用。
      方法  将70例符合脓毒症诊断标准的急危重病症患者随机分为2组, 试验组在西医常规治疗的基础上予以连续7 d口服或鼻饲红玉赔赈颗粒，对照组在西医常规治疗组基础上加用1/10的红玉赔赈颗粒安慰剂，检测2组患者治疗前以及治疗后第1天、第3天、第7天的血清WBC、N%、hs-CRP、ESR、Pct、动脉血Lac水平。
      结果  与对照组比较，治疗后第7天试验组N%、hs-CRP、ESR、PCT、动脉血Lac指标水平均降低更显著(P < 0.05)。
      结论  红玉赔赈颗粒能对脓毒症患者炎症反应起抑制作用，可改善脓毒症患者因组织缺氧及低灌注所致的高乳酸血症，从而改善预后。

     

    Abstract:
      Objective  To investigate effect of Hongyu Peizhen Granule on inflammatory indicators such as white blood cell(WBC), neutrophil percentage (N%), hypersensitive C reaction protein (hs-CRP), erythrocyte sedimentation rate(ESR), serum procalcitonin (PCT), arterial blood lactic acid (Lac) in sepsis patients.
      Methods  Seventy acute and critical illness patients in accordance with the diagnostic criteria of sepsis were randomly divided into two groups. The patients of two groups were all given routine western medicine treatment, the experimental group was orally or nasally given Hongyu Peizhen Granule for 7 consecutive days in addition, while the control group additionally received 1/10 dose of Hongyu Peizhen Granule as placebo. The serum levels of WBC, N%, hs-CRP, ESR, PCT and Lac in arterial blood before treatment, and at 1, 3, 7 d after treatment were measured.
      Results  Compared with the control group, the levels of N%, hs-CRP, ESR, PCT, arterial blood Lac at 7 d in the experimental group decreased more significantly (P < 0.05).
      Conclusion  Hongyu Peizhen Granule can inhibit the inflammatory reaction of sepsis patients and improve their hyperlacticemia caused by tissue hypoxia and hypoperfusion thereby improving the prognosis of sepsis patients.

     

    • HTML全文
    • 参考文献(12)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回