早期镇静剂对小儿热性惊厥癫痫的预防效果

Effect of early sedative on prevention of febrile convulsion epilepsy in children

  • 摘要:
      目的  探讨早期应用镇静剂对小儿热性惊厥癫痫的预防效果。
      方法  选择在本院进行治疗的小儿热性惊厥癫痫患儿146例为研究对象,按照随机数表法将其随机分为对照组和研究组,每组73例。对照组使用对症降温等常规治疗,研究组早期使用镇静剂进行治疗,6个月后,比较2组患儿的临床症状以及预防效果。
      结果  治疗后,研究组癫痫、脑损伤、智力低下的发生率显著低于对照组(P < 0.05); 研究组治愈率显著高于对照组,复发率显著低于对照组(P < 0.05)。
      结论  应用镇静剂对早期小儿热性惊厥癫痫病患儿进行治疗效果明显,可缓解病症,有效预防热性惊厥引起癫痫等并发症,降低复发率。

     

    Abstract:
      Objective  To explore the effect of early sedative in prevention of febrile convulsion epilepsy in children.
      Methods  A total of 146children with febrile convulsion epilepsy who were treated in our hospital were selected as the researchobjects. According to the random number table method, they were randomly divided into control group and research group, with 73 cases in each group. The control group was treated with routine treatment such as symptomatic cooling, while the study group was treated with sedatives at the early stage. After 6 months, the clinical symptoms and preventive effects of the two groups were compared.
      Results  After treatment, the incidences of epilepsy, brain injury and mental retardation in the study group were significantly lower than that in the control group (P < 0.05), and the cure rate in the study group was significantly higher, and recurrence rate was significantly lower than that of the control group(P < 0.05).
      Conclusion  Sedatives are effective in the treatment of early febrile convulsions and epilepsy in children. It can alleviate the symptoms, effectively prevent the seizures caused by febrile convulsions and other complications, and reduce the recurrence rate.

     

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