Abstract: Objective To study the effect of meticulous nursing on the nursing of patients with skin laceration (ST).Methods A total of 120 ST patients were divided into meticulous nursing group and conventional nursing group.The first surgery to skin grafting time,drainage time,hospitalization time and costs of treatment wererecorded and compared.On the day of admission and 7 d after nursing,the SAS and SDS scores were recorded and compared.Nursing satisfaction degree and infection rate 7 d after nursing were recorded and compared.Results In meticulous nursing group,skin grafting time,drainage time and hospital stay were significantly shorter than those in conventional nursing group (P ＜ 0.05).Seven days after nursing,SAS score and SDS score of meticulous nursing group were significantly lower than those on admission day and those of conventional nursing group (P ＜0.01).The satisfaction degree of meticulous nursing group was significantly higher than that of conventional nursing group (P ＜ 0.01).Conclusion Meticulous nursing can significantly improve the prognosis of patients with ST,psychological status and improve the patient's satisfaction degree toward nursing.