Abstract: Objective To explore nursing of postoperative pain patients with complexity retinal detachment.Methods A total of 60 patients with complexity retinal detachment in our hospital were selected as the research objects,and were divided into observation group (30 cases) and control group (30 cases) according to nursing intervention,control group was given comfortable nursing and observation group was given comfortable nursing,curative effects of two groups were contrasted.Resuits There was no significant difference in VAS pain scores on the first postoperative day in two groups (P ＞ 0.05),but VAS pain scores in observation group were significantly lower than the eontrol group on the third and fifth postoperative day,and the difference was statistically significant (P ＜ 0.05).Self-rating depression scale (SDS) score and Self-rating Anxiety Scale (SAS) score of two groups showed no statistically significant difference before operation (P ＞ 0.05),and were showed a significant decrease at discharge,and the observation group decreased more (P ＜ 0.05).There was no statistically significant difference in SF-36 Survival Quality Scale in physiological health,physiological function,the body pain,general health,vitality,social function,emotional function,mental health before operation (P ＞ 0.05),but physical health,physiological function and general health,vitality,social function,emotional function,mental health scores of two groups were significantly higher,and body pain scores were significantly decreased at discharge compared with operation before (P ＜ 0.05),and the indicators of the observation group were significantly higher than that of control group (P ＜ 0.05).Conclusion Comfortable nursing for patients with complexity retinal detachment can significantly relieve patients'pain and improve anxiety and depression,and enhance the quality of survival,so it is worthy of clinical popularization and application.