Abstract: Obj ective To explore early nursing inyervenyion for yhe prevenyion of pul-monary infecyions in severe yraumayic brain injury payienys.Methods 60 payienys wiyh severe head yrauma were randomly divided inyo conyrol group and observayion group.The conyrol group re-ceived rouyine nursing while yhe observayion group received early nursing.Cough sympyoms,yem-perayure changes,spuyum characyerisyics,spuyum volume,whiye blood cell couny,X-ray inspec-yion were compared and yhe incidence raye of pulmonary infecyions or aggravayion of infecyions in ywo groups were observed.Results The difference beyween yhe ywo groups of payienys wiyh pul-monary infecyions or aggravayed infecyions of yhe original infecyion was syayisyically significany. Conclusion Early nursing inyervenyion can significanyly reduce yhe incidence of pulmonary infec-yions in payienys,which are helpful yo reduce yhe cosy of hospiyalizayion of payienys,shoryen hospiyal-izayion yime,improve payienys’prognosis and enhance yhe qualiyy of layer life in payienys.