Abstract: Objective To explore the classification and valuation of postcholecystectomy syndrome (PCS)after open or laparoscopic cholecystectomy.Methods 124 patients with laparo-scopic cholecystectomy (LC group)and 124 patients with cholecystectomy (OC group)were select-ed randomly from 365 patients with follow-up.The conditions of PCS were compared between the two groups after 10 months of surgery.Results The difference of incidence rate of PCS in the LC group (26.6%)and OC group (25.8%)was no statistically significant (P >0.05);The postoper-ative symptoms and the proportion of patients (7.3% in LC group and 0.8% in OC group)requir-ing surgical operation treatment in LC group was higher than that in OC group (P <0.05).The se-vere degree of PCS after operation in LC group was higher than that of OC group.Conclusion LC group has no advantage to reduce the incidence rate of PCS,and the PCS of LC group is more severe than that of OC group.