Abstract: Objective To explore the influence of minimally invasive percutaneous plate psteosynthesis on the postoperative healing and functional recovery of patients with comminuted fracture of proximal end of humerus.Methods Clinical materials of 58 patients with comminuted fracture of proximal end of humerus were analyzed.Results Incision of 58 cases were stage Ⅰheal,the average length of hospital stay was (16.35±2.71)days,fracture healed completely in 55 cases,the average healing time was (13.53±2.64)weeks.3 patients′X-rays showed there was no callus growth.According to Neer scores (100 point scale),the average score of function recov-ery was (85.44±10.95).Different fracture fractal function recovery time and the comparison of type II patients with type Ⅲ had no obvious difference (P <0.05).Conclusion MIPPO has a quite good cure effect on the patient with comminuted fracture of proximal end of humerus.For type Ⅱ and type Ⅲ fracture patients,the efficacy was obviously better than that of type Ⅳ pa-tients.