Abstract: Objective To investigate the rehabilitation nursing procedure and its effects af-ter arthroscopic reconstruction for multiple ligaments injury of knees.Methods 10 patients with multiple ligaments injuries of knee received anterior posterior cruciate ligaments reconstruction by arthroscopy.According to different surgical techniques and individual differences of patients,tar-geted rehabilitation training plans in perioperative period were specifically guided and managed.Pa-tients were followed up to evaluate the clinical effects of training in stages.Results All the patients were regularly followed up foroneweek to2 4 months ,with an average timeof (1 2 .3 0 ± 6.65)months.The difference was statistically significant since the average Lysholm score of the all cases were (26.90±5.07)and (89.50±3.81)before operation and at final follow-up respective-ly(P <0.01).Conclusion Planned and targeted rehabilitation nursing based on the different sur-gical techniques and individual differences can benefit functional recovery of knee joint.It is impor-tant for patients who have arthroscopic reconstruction of multiple ligament injuries to keep on reha-bilitation training after hospita1 discharge.