Abstract: Objective To compare the effect between high-temperature thermoplasticized injectable technique and cold lateral condensation on sealing ability.Methods 68 fresh vitro teeth were divided into group A (30 teeth),group B (30 teeth),positive group (4 teeth)and negative group (4 teeth).Group A was given high-temperature thermoplasticized injectable technique,group B was given cold lateral condensation technique.A root canal filling time,leakage phenomenon, sealing ability and compliance were compared.Results Root canal filling time and seeping into length of group A were significantly lower than those of group B,while sealing capacity and compli-ance were significantly higher than those of group B (P <0.05).Conclusion High-temperature thermoplasticized injectable technique can reduce the filling time,increase compliance and perform a good sealing effect on root canal.